February 2012
| Date | Time | Home Team | Away Team | Venue |
| 22 WED | 5:00PM PST | New England Revolution | LA Galaxy | Kino Stadium |
| 25 SAT | 5:00PM PST | LA Galaxy | Real Salt Lake | Kino Stadium |
| 29 WED | 7:00PM PST | LA Galaxy | New York Red Bulls | Kino Stadium |
March 2012
| Date | Time | Home Team | Away Team | Venue |
| 07 WED | 5:00PM PST | Toronto FC | LA Galaxy | Rogers Centre |
| 10 SAT | 7:30PM PST | LA Galaxy | Real Salt Lake | The Home Depot Center |
| 14 WED | 7:00PM PDT | LA Galaxy | Toronto FC | TBD |
| 18 SUN | 4:00PM PDT | LA Galaxy | D.C. United | The Home Depot Center |
| 31 SAT | 8:00PM PDT | LA Galaxy | New England Revolution | The Home Depot Center |
April 2012
| Date | Time | Home Team | Away Team | Venue |
| 07 SAT | 2:00PM PDT | Sporting KC | LA Galaxy | LIVESTRONG Sporting Park |
| 14 SAT | 7:30PM PDT | LA Galaxy | Portland Timbers | The Home Depot Center |
| 21 SAT | 6:00PM PDT | Colorado Rapids | LA Galaxy | Dick’s Sporting Goods Park |
| 28 SAT | 7:30PM PDT | LA Galaxy | FC Dallas | The Home Depot Center |
May 2012
| Date | Time | Home Team | Away Team | Venue |
| 02 WED | 7:00PM PDT | Seattle Sounders | LA Galaxy | CENTURYLINK Field |
| 05 SAT | 5:00PM PDT | LA Galaxy | New York Red Bulls | The Home Depot Center |
| 12 SAT | 1:00PM PDT | Montreal Impact | LA Galaxy | Olympic Stadium |
| 19 SAT | 7:30PM PDT | Chivas USA | LA Galaxy | The Home Depot Center |
| 23 WED | 7:30PM PDT | LA Galaxy | San Jose Earthquakes | The Home Depot Center |
| 26 SAT | 11:30PM PDT | Houston Dynamo | LA Galaxy | BBVA Compass Stadium |
June 2012
| Date | Time | Home Team | Away Team | Venue |
| 17 SUN | 4:00PM PDT | LA Galaxy | Portland Timbers | The Home Depot Center |
| 20 WED | 6:00PM PDT | Real Salt Lake | LA Galxy | Rio Tinto Stadium |
| 23 SAT | 7:30PM PDT | LA Galxy | Vancouver Whitecaps FC | The Home Depot Center |
| 30 SAT | 7:00PM PDT | San Jose Earthquakes | LA Galxy | Stanford Stadium |
July 2012
| Date | Time | Home Team | Away Team | Venue |
| 04 WED | 7:30PM PDT | LA Galaxy | Philadelphia Union | The Home Depot Center |
| 08 SUN | 12:00PM PDT | Chicago Fire | LA Galaxy | TOYOTA Park |
| 14 SAT | 8:00PM PDT | Portland Timbers | LA Galaxy | JELD-WEN Field |
| 18 WED | 7:00PM PDT | Vancouver Whitecaps | LA Galaxy | BC Place |
| 21 SAT | 7:00PM PDT | LA Galaxy | Chivas USA | The Home Depot Center |
| 28 SAT | 5:00PM PDT | FC Dallas | LA Galaxy | FC Dallas Stadium |
August 2012
| Date | Time | Home Team | Away Team | Venue |
| 05 SUN | 7:00PM PDT | Seattle Sounders FC | LA Galaxy | CenturyLink Field |
| 12 SUN | 8:00PM PDT | Chivas USA | LA Galaxy | The Home Depot Center |
| 15 WED | 5:00PM PDT | Columbus Crew | LA Galaxy | Crew Stadium |
| 26 SUN | 4:00PM PDT | LA Galaxy | FC Dallas | The Home Depot Center |
September 2012
| Date | Time | Home Team | Away Team | Venue |
| 01 SAT | 7:00PM PDT | LA Galaxy | Vancouver Whitecaps FC | The Home Depot Center |
| 16 SUN | 4:00PM PDT | LA Galaxy | Colorado Rapids | The Home Depot Center |
| 22 SAT | 7:30PM PDT | LA Galaxy | Toronto FC | The Home Depot Center |
| 30 SAT | 4:00PM PDT | Colorado Rapids | LA Galaxy | Dick’s Sporting Goods Park |
October 2012
| Date | Time | Home Team | Away Team | Venue |
| 06 SAT | 6:00PM PDT | LA Galaxy | Real Salt Lake | The Home Depot Center |
| 21 SUN | 4:00PM PDT | San Jose Earthquakes | LA Galaxy | Buck Shaw Stadium |
| 28 SUN | 6:00PM PDT | LA Galaxy | Seattle Sounders | The Home Depot Center |