February 2012
| Date | Time | Home Team | Away Team | Venue |
| 27 MON | 5:00PM PST | Chivas USA | Alk | JELD-WEN Field Preseason |
| 27 MON | 7:30PM PST | Portland | San Jose | JELD-WEN Field Preseason |
March 2012
| Date | Time | Home Team | Away Team | Venue |
| 01 THU | 5:00PM PST | Alk | San Jose | JELD-WEN Field Preseason |
| 01 THU | 7:30PM PST | Portland | Chivas USA | JELD-WEN Field Preseason |
| 04 SUN | 2:30PM PST | San Jose | Chivas USA | JELD-WEN Field Preseason |
| 04 SUN | 5:00PM PST | Portland | Alk | JELD-WEN Field Preseason |
| 12 MON | 6:30PM PDT | Portland | Philadelphia | JELD-WEN Field |
| 17 SAT | 5:30PM PDT | FC Dallas | Portland | FC Dallas Stadium |
| 24 SAT | 1:00PM PDT | New England | Portland | Gillette Stadium |
| 31 SAT | 7:00PM PDT | Portland | Real Salt Lake | JELD-WEN Field |
April 2012
| Date | Time | Home Team | Away Team | Venue |
| 07 SAT | 7:30PM PDT | Portland | Chivas USA | JELD-WEN Field |
| 14 SAT | 7:30PM PDT | Los Angeles | Portland | The Home Depot Center |
| 21 SAT | 7:30PM PDT | Portland | Sporting KC | JELD-WEN Field |
| 28 SAT | 11:00AM PDT | Montreal | Portland | Stade Olympique |
May 2012
| Date | Time | Home Team | Away Team | Venue |
| 05 SAT | 7:30PM PDT | Portland | Columbus | JELD-WEN Field |
| 15 TUE | 5:30PM PDT | Houston | Portland | BBVA Compass Stadium |
| 20 SUN | 4:00PM PDT | Portland | Chicago | JELD-WEN Field |
| 26 SAT | 7:00PM PDT | Portland | Vancouver | JELD-WEN Field |
June 2012
| Date | Time | Home Team | Away Team | Venue |
| 17 SUN | 4:00PM PDT | Los Angeles | Portland | Home Depot Center |
| 24 SUN | 2:00PM PDT | Portland | Seattle | JELD-WEN Field |
| 30 SAT | 6:00PM PDT | Colorado | Portland | Dick’s Sporting Goods Park |
July 2012
| Date | Time | Home Team | Away Team | Venue |
| 03 TUE | 7:30PM PDT | Portland | San Jose | JELD-WEN Field |
| 07 SAT | 6:00PM PDT | Real Salt Lake | Portland | Rio Tinto Stadium |
| 14 SAT | 8:00PM PDT | Portland | Los Angeles | JELD-WEN Field |
| 18 WED | 1:00PM PDT | Chivas USA | Portland | The Home Depot Center |
| 21 SAT | 6:00PM PDT | FC Dallas | Portland | FC Dallas |
| 28 SAT | 8:00PM PDT | Portland | Chivas USA | JELD-WEN Field |
August 2012
| Date | Time | Home Team | Away Team | Venue |
| 05 SUN | 4:00PM PDT | Portland | FC Dallas | JELD-WEN Field |
| 15 WED | 4:00PM PDT | Toronto FC | Portland | BMO Stadium |
| 19 SUN | 4:00PM PDT | New York | Portland | Red Bull Arena |
| 25 SAT | 7:30PM PDT | Portland | Vancouver | JELD-WEN Field |
| 31 FRI | 7:30PM PDT | Portland | Colorado | JELD-WEN Field |
September 2012
| Date | Time | Home Team | Away Team | Venue |
| 05 WED | 6:00PM PDT | Colorado | Portland | Dick’s Sporting Goods Park |
| 15 SAT | 12:30PM PDT | Portland | Seattle | JELD-WEN Field |
| 19 WED | 7:30PM PDT | San Jose | Portland | Buck Shaw Stadium |
| 22 SAT | 5:00PM PDT | Real Salt Lake | Portland | PPL Park |
| 29 SAT | 7:30PM PDT | Portland | D.C. United | JELD-WEN Field |
October 2012
| Date | Time | Home Team | Away Team | Venue |
| 07 SUN | 6:00PM PDT | Seattle | Portland | Century Link Field |
| 20 SAT | 1:00PM PDT | Vancouver | Portland | BC Place |
| 27 SAT | 3:30PM PDT | Portland | San Jose | JELD-WEN Field |