March 2012
| Date | Time | Home Team | Away Team | Venue |
| 10 SAT | 7:30PM PST | San Jose | New England | Buck Shaw Stadium |
| 18 SUN | TBD | San Jose | Houston | Buck Shaw Stadium |
| 24 SAT | 10:00PM PDT | Toronto FC | San Jose | BMO Field |
| 31 SAT | 7:00PM PDT | Seattle | San Jose | CentruryLink Field |
April 2012
| Date | Time | Home Team | Away Team | Venue |
| 07 SAT | 7:30PM PDT | San Jose | Vancouver | Buck Shaw Stadium |
| 14 SAT | 4:00PM PDT | New York | San Jose | Red bull Arena |
| 21 SAT | 7:30PM PDT | San Jose | Real Salt Lake | Buck Shaw Stadium |
| 28 SAT | 4:00AM PDT | Philadelphia | San Jose | PPL Park |
May 2012
| Date | Time | Home Team | Away Team | Venue |
| 02 SAT | 7:30PM PDT | San Jose | D.C. United | Buck Shaw Stadium |
| 05 TUE | 4:00PM PDT | Vancouver | San Jose | BC Place |
| 13 WED | 4:00PM PDT | San Jose | Chivas USA | Buck Shaw Stadium |
| 19 TUE | 7:30PM PDT | San Jose | Columbus | Buck Shaw Stadium |
| 23 SAT | 7:30PM PDT | Los Angeles | San Jose | Home Depot Center |
| 27 WED | 1:30PM PDT | Sporting KC | San Jose | LiveStrong Sporting Park |
June 2012
| Date | Time | Home Team | Away Team | Venue |
| 20 WED | 6:30PM PDT | Colorado | San Jose | Dick’s Sporting Goods Park |
| 23 SAT | 6:00PM PDT | Real Salt Lake | San Jose | Rio Tinto Stadium |
| 30 SAT | 7:00PM PDT | San Jose | Los Angeles | Stanford Stadium |
July 2012
| Date | Time | Home Team | Away Team | Venue |
| 03 TUE | 7:30PM PDT | Portland | San Jose | JELD-WEN Field |
| 07 SAT | 6:00PM PDT | FC Dallas | San Jose | FC Dallas |
| 14 SAT | 7:30PM PDT | San Jose | Real Salt Lake | Buck Shaw Stadium |
| 18 WED | 7:30PM PDT | San Jose | FC Dallas | Buck Shaw Stadium |
| 22 SUN | 4:00PM PDT | Vancouver | San Jose | BC Place |
| 28 SAT | 7:30PM PDT | San Jose | Chicago | Buck Shaw Stadium |
August 2012
| Date | Time | Home Team | Away Team | Venue |
| 11 SAT | 7:30PM PDT | San Jose | Seattle | Buck Shaw Stadium |
| 18 SAT | 4:30PM PDT | Montreal | San Jose | Saputo Stadium |
| 25 SAT | 7:30PM PDT | San Jose | Colorado | Buck Shaw Stadium |
September 2012
| Date | Time | Home Team | Away Team | Venue |
| 02 SUN | 6:00PM PDT | San Jose | Chivas USA | Buck Shaw Stadium |
| 15 SAT | 7:30PM PDT | Chivas USA | San Jose | Home Depot Center |
| 19 WED | 7:30PM PDT | San Jose | Portland | Buck Shaw Stadium |
| 23 SUN | 4:00PM PDT | Seattle | San Jose | CenturyLink Field |
| 29 SAT | 7:30PM PDT | San Jose | FC Dallas | Buck Shaw Stadium |
October 2012
| Date | Time | Home Team | Away Team | Venue |
| 06 SAT | 6:00PM PDT | Colorado | San Jose | Dick’s Sporting Goods Park |
| 21 SUN | 4:00PM PDT | San Jose | Los Angeles | Buck Shaw Stadium |
| 27 SAT | 3:30PM PDT | Portland | San Jose | JELD-WEN Field |